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QUICK ANSWER
"Cuando estás de vacaciones" is a form of "cuando estás de vacaciones", a phrase which is often translated as "when you're on vacation". "Qué haces" is a form of "qué haces", a phrase which is often translated as "what you're doing". Learn more about the difference between "cuando estás de vacaciones" and "qué haces" below.
cuando estás de vacaciones(
kwahn
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doh
ehs
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tahs
deh
bah
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kah
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syoh
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nehs
)A phrase is a group of words commonly used together (e.g., once upon a time).
1. (informal) (second person singular)
A word or phrase used to refer to the second person informal “tú” by their conjugation or implied context (e.g., How are you?).
a. when you're on vacation (United States)
Regionalism used in the United States
Se te ve tan relajado cuando estás de vacaciones.You look so relaxed when you're on vacation.
b. when you're on holiday (United Kingdom)
Regionalism used in the United Kingdom
¿A qué hora te levantas cuando estás de vacaciones?What time do you get up when you're on holiday?
qué haces(
keh
ah
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sehs
)A phrase is a group of words commonly used together (e.g., once upon a time).
1. (informal) (singular)
A word or phrase used to refer to the second person informal “tú” by their conjugation or implied context (e.g., How are you?).